About the Lab

The Siliciano Lab is a research lab led by Drs. Robert and Janet Siliciano at the Johns Hopkins University School of Medicine.

What we study

We, as a lab, are dedicated to studying the dynamics and persistence of the HIV latent reservoir and ways in which to overcome this barrier to a cure.

To learn more about the specifics of our areas of research, please check out the research tab.

Decay of the latent reservoir during very long-term ART
(McMyn et al. 2023)

Phylogenetic relationship between antibody-sensitive and
antibody-resistant QVOA isolates (Bertagnolli et al. 2020)

Effect of slope (m) on dose-response curves of antiretroviral drugs
(Shen et al. 2008)

HIV-1–infected, CMV-responding cells are enriched in proviral
populations generated by clonal expansion
(Simonetti et al. 2021)

Cognate antigen engagement induces HIV-1 expression
in latently infected CD4+ T cells from people on longterm
antiretroviral therapy (Moskovljevic et al. 2024)

Bispecific antibodies promote natural killer
cell-mediated elimination of HIV-1reservoir cells
(Board et al. 2023)